In this procedure, the target area is marked out manually. The machine also uses a strong vacuum that helps to stop the blood flow and pull away heat from the blood. The cool plate is then placed on the target area that will feel a pulling effect and a pinching sensation. Further, the lipids present in the adipocytes are crystallized, and they interact with the cell membrane. The temperature inside the applicator is lowered and reaches a minimum of -3 to -8 degree centigrade. This slowly freezes the fat cells. As temperature decreases, the skin becomes numb, and the patient experiences no pinching sensation. The whole procedure takes about 40 to 80 minutes, depending upon the target area. On the first day of treatment, adipocytes appear normal, and after that, a light inflammation can be seen. The macrophages digest the adipocytes or cell content released by them.